Sociodemographic and Clinical factors associated with Preterm Premature Rupture of Membranes among Pregnant Women admitted to Public Hospitals of West Shewa Zone, Central Ethiopia

Abstract

Background: Preterm Premature Rupture of Membranes (PPROM) poses a critical public health challenge, especially in low- and middle-income countries where it leads to substantial maternal and perinatal morbidity and mortality. However, the specific factors influencing PPROM have not been well understood in Ethiopia. Therefore, this study sought to uncover factors associated with PPROM among Pregnant Women admitted to Public Hospitals of West Shewa Zone, Central Ethiopia.

Methods: A hospital-based unmatched case-control study was conducted from January 1 to February 28, 2024, involving 142 cases and 284 controls. Data were analyzed using SPSS software. Bivariate and multivariable logistic regression analyses were performed to assess the relationship between dependent and independent variables, with statistical significance set at a p-value < 0.05.

Results: Middle Upper Arm Circumference < 23 cm [AOR = 4.38, 95% CI: 4.05-13.4], Rural residence [AOR=1.74, 95% CI: 1.33-4.64], pre-eclampsia during current pregnancy [AOR = 4.82, 95% CI: 1.78-13.1], and having a history of genital tract infection during this pregnancy [AOR = 2.02, 95% CI: 1.88-4.63] was found to be significant predictors of PPROM.

Conclusion: Early identification and management of these factors are crucial for reducing PPROM risk, alongside enhancing nutritional counseling during pregnancy.